Nearly 20% of children with NF1 develop pLGGs along the optic pathway, also known as NF1-associated optic pathway glioma (NF1-OPG). Despite many advances in cancer therapy, there are no definitive ...
Girl diagnosed with neurofibromatosis type 1 had chemotherapy to prevent going blind from optic pathway gliomas, NF1 tumors ...
A Scientific Online Poster presented during the 2023 ARRS Annual Meeting, held April 16–20 on the island of Oahu, explained how the novel technique of three-dimensional (3D) slice-to-volume (SVR) MRI ...
The interplay between experimental autoimmunity and neural degeneration within optic pathways underpins the pathogenesis of optic neuritis and related demyelinating disorders. In preclinical models ...
Phase 1/2 study of elraglusib (9-ING-41), a small molecule selective glycogen synthase kinase-3 beta (GSK-3β) inhibitor, alone or with irinotecan, temozolomide ...
Optic glioma is a brain tumor that grows slowly. Around 75% of diagnoses occur in children younger than 10 years old. Optic glioma accounts for approximately 5% of all childhood brain tumors. The ...
It has been several months since Dr. Lane Rutledge, who was our colleague in the UAB NF Clinic, passed away unexpectedly, and her absence has been felt by those of us in the NF Clinic as well as by ...
Impact of bevacizumab added to temozolomide-chemoradiation on time to health-related quality of life deterioration in unresectable glioblastoma: Results of a phase II randomized clinical trial. This ...
An award-winning presentation during the 2023 ARRS Annual Meeting explained how the novel technique of three-dimensional (3D) slice-to-volume (SVR) MRI allows for precise delineation and measurement ...
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