Iron is essential for cellular respiration, DNA synthesis and numerous enzymatic reactions. Its transport in vertebrates relies on the iron‐binding glycoprotein transferrin, which circulates in plasma ...
Iron is indispensable for oxygen transport, DNA synthesis and energy production, yet free iron is potentially toxic. Cellular uptake of iron is primarily mediated by the transferrin receptor (TfR), ...
NEW YORK--(BUSINESS WIRE)--Apertura Gene Therapy, a biotechnology company opening opportunities in genetic medicine for treating debilitating diseases with limited options, today unveiled its ...
A newly engineered antibody transport vehicle targeting the transferrin receptor enables enhanced delivery of anti-amyloid antibodies to the brains of mouse models of Alzheimer's disease, researchers ...
This new article publication from Acta Pharmaceutica Sinica B, discusses a transferrin receptor-targeted immunostimulant for photodynamic immunotherapy against metastatic tumors through β-catenin/CREB ...
The blood-brain border has long stymied drug development for neurodegenerative diseases. In recent years, Denali, Roche, and others have designed molecular brain shuttles that ferry investigational ...
According to the American Brain Foundation, over one in three people around the world are affected by neurological conditions, the leading cause of illness and disability worldwide. This silent ...
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